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SKINVIVE™

Models treated with SKINVIVE™.
Individual results may vary.

Healthy-looking skin starts with hydration3

Now, more than ever, we are interested in healthy-looking skin.4 From its surface texture and tone (colour) to elasticity and glow, for our skin to look its best, hydration is essential.3,5,6

When hyaluronic acid levels decrease due to environmental factors or with age, this can lead to visible changes such as skin roughness, a loss of firmness, and the appearance of fine lines and wrinkles.1,2

The good news is that by delivering hyaluronic acid where it can make a real difference,7 you can improve hydration‖ and start your journey to healthy-looking§ skin.2

What is SKINVIVE™?

Deep, long-lasting** skin hydration* from within1

SKINVIVE™ is a hyaluronic acid skin hydration injection that can be injected into the face, décolletage, neck, and hands7,8,20 to help deliver deep long-lasting** hydration* and visibly reduce the appearance of fine lines.7,* It hydrates* and refreshes†† from within1,2,9,‡‡ for radiant,† smooth‡ and healthy-looking§ skin.2

A hyaluronic acid injection unlike any other9

Designed with patented technology2 from the world’s #1 brand of hyaluronic acid facial fillers,10,§§ SKINVIVE™ contains a thinner form of hyaluronic acid that easily spreads within the skin.11,12 This makes it different to other hyaluronic acid facial filler injections used to increase volume or re-contour the face.11,12

As the only hyaluronic acid injection clinically proven to boost skin hydration* for up to 9 months,1,10,‖‖ hydrated,* healthy-looking skin§ is just one treatment away with SKINVIVE™.7,¶¶

¶¶ A touch up treatment may be required at the clinician’s discretion.1

How is SKINVIVE™ different to topical moisturisers?

Unlike topical moisturisers – like hyaluronic acid creams and serums – that only target the surface,13 SKINVIVE™ targets the deeper layers of your skin to help achieve healthy looking§, long-lasting** results.1,2,7

Topical moisturisers

Topical moisturisers only hydrate the surface layers of the skin and have to be applied frequently.13

SKINVIVE™ is injected into the deeper layers of the skin, delivering hyaluronic acid where it can make a real difference.1,14

SKINVIVE™ boosts levels of aquaporin-39,‡‡ a naturally-occurring molecule that helps maintain water balance in the skin. Increases in aquaporin signal an increase in hydration.10,15

Boost your daily skincare routine with SKINVIVE™

By helping to deliver deep, long-lasting** hydration,1,* SKINVIVE™ supports your existing skincare routine, including your daily cleansing, exfoliating, toning, moisturising and sun protection.16

DAILY SKINCARE ROUTINE

Cleansing

Moisturising

Exfoliating

Sun protection

Toning

HYALURONIC ACID INJECTION

Deep hydration1,*

Smooth,‡ glowing† and healthy-looking§ skin2

See the SKINVIVE™ difference up close

Discover high-definition Before & After photos of real patients and
see transformative‡‡‡ skin hydration1,§ results with SKINVIVE™.

EXPLORE BEFORE & AFTERS

Reference: 

a. Niforos F et al. Clin Cosmet Investig Dermatol. 2019;12:791–798.

 

Footnotes:

¥ Individual results may vary.

Δ Instrument measures of skin hydration, smoothness, and skin deformation parameters were performed on the cheek, forehead, and neck of one side of the face on Day 0 and at 30 days after initial treatment (before touch up), Months 1, 4, 6, and 9 after the last treatment, and Month 1R. Skin hydration was measured using the MoistureMeterD instrument (n=131) and top-up treatment administered at Day 30 (n=31) to correct asymmetry.a

 

 

Find your nearest clinic

For a deep, long-lasting** injectable skin hydration* treatment that helps you meet your individual beauty goals,1,7,17,18 speak to your aesthetic healthcare practitioner about SKINVIVE™.

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ENDPOINT

SKINVIVE™ is a hyaluronic acid injectable treatment which deeply hydrates* the skin to enhance texture,‡ tone (colour),*** and radiance† of the face, neck, hands, and décolletage.1,2,19

Footnotes

  • *Instrument measures of skin hydration, smoothness, and skin deformation parameters were performed on the cheek, forehead, and neck of one side of the face on Day 0 and at 30 days after initial treatment (before touch up), Months 1, 4, 6, and 9 after the last treatment, and Month 1R. Skin hydration was measured using the MoistureMeterD instrument (n=131) and top-up treatment administered at Day 30 (n=31) to correct asymmetry.1
  • †Lasting up to 9 months as reported by 63% of patients (from a subset of 127 patients at 9 months; n=131 initially enrolled) in a composite satisfaction score, including how radiant their facial skin looked.2
  • ‡Lasting up to 9 months, as reported by 55.1% of patients (from a subset of 127 patients at 9 months; n=131 initially enrolled) in a composite satisfaction score, including how smooth their facial skin looked.2
  • §Lasting up to 9 months as reported by 76.2% of patients (from a subset of 127 patients at 9 months; 1 subject did not respond; n=131 initially enrolled) in a composite satisfaction score, which includes how healthy their facial skin looked.2
  • ‖Lasting up to 9 months as reported by 70.6% of patients (from a subset of 127 patients at 9 months; 1 subject did not respond; n=131 initially enrolled) in a composite satisfaction score, including how hydrated their facial skin looked.2
  • Skin hydration was measured using the MoistureMeterD instrument with the XS 5 and S 15 probes (depth of effective measurement: 0.5 and 1.5 mm, respectively).1
  • **Long lasting is up to 9 months following a single treatment.1
  • ††Lasting up to 9 months as reported by 51.2% of patients (from a subset of 127 patients at 9 months; 2 subjects did not respond; n=131 initially enrolled) in a composite satisfaction score, which includes how refreshed their facial skin looked.2
  • ‡‡Data derived from a prospective, non-randomised, interventional, open-label study where 11 healthy patients (men [n=2] and women [n=9]) received intradermal VYC-12L treatment on the volar forearm. Clinical probes assessed skin quality at baseline and Months 1 and 3 post-treatment. Punch biopsies were collected at Months 1 and 3 post-treatment to evaluate histologic and genomic changes.9
  • §§Based on HCP tracking market research involving over 1,700 HCPs from 16 international markets.11
  • ‖‖Based on a search of published clinical studies of injectable HA treatments in March 2023. A duration of 9 months was established with SKINVIVE™.10
  • ¶¶A touch up treatment may be required at the clinician’s discretion.1,2,7,10
  • ***Individual results may vary.

 

References

  1. Niforos F et al. Clin Cosmet Investig Dermatol. 2019;12:791–798.
  2. Ogilvie P et al. J Cosmet Dermatol. 2020;19(5):1065–1070.
  3. Humphrey S et al. Dermatol Surg. 2021;47(7):974–981.
  4. Allergan Aesthetics. Data on file. Skin Health Statistics. REF-100241. August 2022.
  5. Fisher GJ et al. Arch Dermatol. 2008;144:666–672.
  6. Walker M. Int J Pharm. 2022;622:121850.
  7. SKINVIVE™ by JUVÉDERM® DFU. 20081699. Revision 2023-10-04.
  8. Allergan Aesthetics. Data on File. Juvéderm® VOLITE Treatment Area. REF-80815. March 2019.
  9. Safa M et al. Clin Cosmet Investig Dermatol. 2022;15:411–426.
  10. Allergan Aesthetics. Data on File. SKINVIVE™ by JUVÉDERM® – 9-month duration of skin hydration in clinical trials. REF-108945. March 2023.
  11. Allergan Aesthetics. Data on File. JUVÉDERM®, the world’s leading brand of hyaluronic acid facial fillers. REF-108642. March 2023.
  12. Akinbiyi T et al. Plast Reconstr Surg Glob Open. 2020;8(10):e2763.
  13. Lipko-Godlewska S et al. Clin Cosmet Investig Dermatol. 2021;14:169–178.
  14. Purnamawati S et al. Clin Med Res. 2017;15(3-4);75–87.
  15. Belmontesi M, et al. J Drugs Dermatol. 2018 Jan 1;17(1):83-88.
  16. Draelos Z. J Clin Aesthet Dermatol. 2012;5(7):53–56.
  17. Khmaladze I et al. Clin Cosmet Investig Dermatol. 2020;13:1021–1040.
  18. Zarbafian M et al. Dermatol Surg. 2022;48(3):369–372.
  19. Alexiades M et al. Dermatol Surg. 2023;49(7):682–688.
  20. Ogilvie P et al. Clin Cosmet Investig Dermatol. 2020;13:267–274. 

 

The information on this website is intended for informational and educational purposes only and should not be used as a substitute for advice provided by a qualified aesthetic healthcare professional.

Models received a variety of JUVÉDERM® products, including SKINVIVE™ by JUVÉDERM®. Images provided courtesy of Allergan Aesthetics, an AbbVie company (unless stated otherwise). Actual treatment results may vary. Images are for illustrative purposes only.

Website produced and funded by Allergan Aesthetics, an AbbVie company.

IMPORTANT SAFETY INFORMATION

This content is intended for UK and Irish adult (>18yrs) audiences only. You should always consult a healthcare professional to help you decide if SKINVIVE™ by JUVÉDERM® is right for you and provide you with a full list of potential side effects.

Potential side effects associated with SKINVIVE™ by JUVÉDERM® include temporary injection-site reactions such as redness, swelling, itching, pain, firmness, bumps, bruising, and discolouration. These reactions may occur immediately or may be delayed. As with any injection, there is a risk of infection. This is not a complete list of side effects. If inflammatory reactions persist for more than one week, or if any other side effects develop, seek medical attention as soon as possible.7

Please refer to SKINVIVE by JUVÉDERM® Directions for use (DFU) for a full list of indications, contraindications, precautions for use, and adverse events.

Adverse events should be reported. 

 

Reporting of side effects:

UK patients: If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in the package leaflet. You can help by reporting side effects directly via the Yellow Card Scheme at https://yellowcard.mhra.gov.uk/ or via the MHRA Yellow Card app, available in the Google Play or Apple App Stores. Adverse events should also be reported to AbbVie at ProductSurveillance_EAME@allergan.com. By reporting side effects, you can help provide more information on the safety of this product.

 

Irish patients: If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in the package leaflet. You can also report side effects directly via www.hpra.ie.

UK-SKV-250022 | September 2025