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SKINVIVE™
frequently asked questions

Models treated with SKINVIVETM.
Individual results may vary.

In this section, you can find answers to some common questions about SKINVIVE™. If you have any other questions or would like to know if SKINVIVE™ could be right for you, our clinic locator tool can help find an aesthetic healthcare practitioner in your area.

SKINVIVE™ is a smooth hyaluronic acid gel1 specifically designed2 to hydrate* and refresh§ your skin.2,3

Unlike topical moisturisers, SKINVIVE™ delivers hyaluronic acid into the deeper‖ layers of your skin1, so you can achieve long-lasting hydration* for up to 9 months.3,4

SKINVIVE™ can be used to treat the face, neck, hands, and décolletage area.1,5,16

SKINVIVE™ hyaluronic acid injections are suitable for all Fitzpatrick skin types.3,6**  So, if you're looking to improve your skin's clarity,†† smoothness,‡‡ hydration,* radiance‡  or tone (colour),§§  SKINVIVE™ could be right for you.2

A single SKINVIVE™ treatment# can provide deep,‖ long-lasting hydration* for up to 9 months.3 It can also visibly reduce fine lines* with results that last up to 4 months.3

# A touch up treatment may be required at the clinician’s discretion.1

Creams and serums containing hyaluronic acid are applied topically.4 This means they often have to be applied frequently, because they only hydrate the surface layers of the skin.4

In contrast, hyaluronic acid injections like SKINVIVE™ target the deeper‖ layers of your skin,1,3 and help to deliver hyaluronic acid where it can help to make a real difference.1,3 This means they can help to offer long-lasting, deep‖ hydration.3,*

Designed for skin hydration, SKINVIVE™ contains a thinner form of hyaluronic acid that easily spreads to deeply‖ hydrate* skin from within.3,7,8 This is different to facial fillers that have a thicker form of hyaluronic acid, which is more suitable to increase volume or re-contour the face. 7,8

SKINVIVE™ can complement your existing skincare routine, adding deep‖ hydration* alongside your daily cleansing, exfoliating, moisturising and sun protection3,9,10,‖‖,¶¶ – so you can enjoy hydrated,* glowing‡ skin day in, day out. 2,3

After treatment, you can expect to see results within the first month.3 SKINVIVE™ then keeps on working for up to 9 months so you can enjoy a long-lasting glow‡ day in, day out2.

If you’re looking to improve dull or rough skin, SKINVIVE™ could help.2 By unleashing deep,‖ long-lasting hydration,* SKINVIVETM could help you achieve smooth,‡‡ glowing,‡  and healthy-looking† skin.2,3

When skin is dehydrated, it often appears rough in texture.11 By boosting skin hydration* with SKINVIVE™, you could enjoy touchably smooth‡‡ skin for up to 6 months with just one treatment.2,3,‖,#

If you're looking to tackle fine lines* on your face, décolletage, neck, or hands, SKINVIVE™ could help.1,5,16 Treatment has been shown to visibly reduce fine lines*, with results that last up to 4 months.3

If you’re looking to achieve a more even skin tone§§, SKINVIVE™ could help.2 By helping to deliver hyaluronic acid into the deeper‖ layers of the skin,1 SKINVIVE™ has been shown to not only improve skin tone (colour),§§ but also smoothness,‡‡ clarity,†† radiance‡ and hydration.2,3,*

When skin is dehydrated, it often appears visibly dry and dull.11 SKINVIVE™ helps to deliver hyaluronic acid into the deeper‖ layers of the skin where it could make a real difference.3,12

It also boosts levels of aquaporin-313,** – a naturally occurring molecule that helps maintain water balance in the skin. Increases in aquaporin-3 signal an increase in hydration.13,14

Through this deep‖ hydration,* SKINVIVE can help you to achieve a healthy-looking† glow‡  for up to 9 months.2,3

SKINVIVE™ can fit into your wider aesthetic treatment plan, whether that includes other fillers, fat-dissolving injections, or body contouring.9,10,‖‖,¶¶

¶¶ SKINVIVE™ should not be used simultaneously with laser treatment, deep chemical peels or dermabrasion. For surface peels, it is recommended not to inject the product if the inflammatory reaction generated is significant.1

To make your experience as comfortable as possible, SKINVIVE™ contains lidocaine, a mild local anaesthetic.1

Like all medical procedures, treatment with hyaluronic acid injections may cause side effects.1 For SKINVIVE™, these may include inflammatory reactions such as redness and swelling, bruising, lumps, thickening and hardening of skin and discolouration at the site of injection.1

These injection-site reactions are mainly mild or moderate and typically resolve within 1 week.3

This is not a complete list of side effects. You should always consult a healthcare professional to help you decide if SKINVIVE™ by JUVÉDERM® is right for you and provide you with a full list of potential side effects.

Treatment with SKINVIVETM may cause injection-site reactions.1 However, a registered healthcare professional specialised in facial aesthetics will be trained to reduce the risk of side effects, like bruising or lumps.1

For 12 hours after SKINVIVE™ treatment, you should avoid using make-up.1

For 2 weeks after SKINVIVE™ treatment, you should avoid any extended exposure to the sun, UV rays or temperatures below 0°C.4 You should also avoid any sauna or steam room (hammam) sessions during this time.1

See the SKINVIVE™ difference up close

Discover high-definition Before & After photos of real patients and
see transformative‡‡‡ skin hydration1,§ results with SKINVIVE™.

EXPLORE BEFORE & AFTERS

Reference: 

a. Niforos F et al. Clin Cosmet Investig Dermatol. 2019;12:791–798.

 

Footnotes:

¥ Individual results may vary.

Δ Instrument measures of skin hydration, smoothness, and skin deformation parameters were performed on the cheek, forehead, and neck of one side of the face on Day 0 and at 30 days after initial treatment (before touch up), Months 1, 4, 6, and 9 after the last treatment, and Month 1R. Skin hydration was measured using the MoistureMeterD instrument (n=131) and top-up treatment administered at Day 30 (n=31) to correct asymmetry.a

 

 

Find your nearest clinic

For a deep,‖ long-lasting¶¶ injectable skin hydration* treatment that helps you meet your individual beauty goals, speak to your aesthetic healthcare practitioner about SKINVIVE™.1,3,6,10

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Footnotes

  • *Instrument measures of skin hydration, smoothness, and skin deformation parameters were performed on the cheek, forehead, and neck of one side of the face on Day 0 and at 30 days after initial treatment (before touch up), Months 1, 4, 6, and 9 after the last treatment, and Month 1R. Skin hydration was measured using the MoistureMeterD instrument (n=131) and top-up treatment administered at Day 30 (n=31) to correct asymmetry.3
  • †Lasting up to 9 months as reported by 76.2% of patients (from a subset of 127 patients at 9 months; 1 subject did not respond; n=131 initially enrolled) in a composite satisfaction score, which includes how healthy their facial skin looked.2
  • ‡Lasting up to 9 months as reported by 63% of patients (from a subset of 127 patients at 9 months; n=131 initially enrolled) in a composite satisfaction score, including how radiant their facial skin looked.2
  • §Lasting up to 9 months as reported by 51.2% of patients (from a subset of 127 patients at 9 months; 2 subjects did not respond; n=131 initially enrolled) in a composite satisfaction score, which includes how refreshed their facial skin looked.2
  • #A touch up treatment may be required at the clinician’s discretion.1-3,15
  • ‖Skin hydration was measured using the MoistureMeterD instrument with the XS 5 and S 15 probes (depth of effective measurement: 0.5 and 1.5 mm, respectively).3
  • Long lasting is up to 9 months following a single treatment.3
  • **The Fitzpatrick classification denotes six different skin types, skin colour and reaction to sun exposure (type I: burns easily, never tans; type II: burns easily, tans minimally with difficulty; type III: burns moderately, tans moderately and uniformly; type IV: burns minimally, tans moderately and easily; type V: rarely burns, tans profusely; type VI: never burns, tans profusely).7 In a randomised, evaluator-blind, delayed treatment control study involving 209 patients, the majority of patients had Fitzpatrick skin types III/IV (58.8%), followed by I/II (32.0%) and V/VI (9.2%).6 In a prospective, single-arm study of 131 patients, the majority of patients had Fitzpatrick skin type III (53.4%), followed by II (35.1%), IV (10.7%) and V (0.8%).3
  • ††Lasting up to 9 months as reported by 64.6% of patients (from a subset of 127 patients at 9 months; n=131 initially enrolled) in a composite satisfaction score, including how clear their facial skin looked.2
  • ‡‡Lasting up to 9 months, as reported by 55.1% of patients (from a subset of 127 patients at 9 months; n=131 initially enrolled) in a composite satisfaction score, including how smooth their facial skin looked.2
  • §§Lasting up to 9 months, as reported by 67.7% of patients (from a subset of 127 patients at 9 months; 3 subjects did not respond; n=131 initially enrolled) in a composite satisfaction score, including satisfaction with their skin’s tone (colour).2
  • ‖‖SKINVIVE™ must not be used in: patients suffering from untreated epilepsy; patients who tend to develop hypertrophic scarring; patients with known hypersensitivity to hyaluronic acid and/or to gram positive bacterial proteins as hyaluronic acid is produced by Streptococcus type bacteria; patients with known hypersensitivity to lidocaine or to amide-type local anaesthetics; patients suffering from porphyria; women who are pregnant or breastfeeding; children. SKINVIVE™ must not be used in areas presenting cutaneous inflammatory and/or infectious processes (acne, herpes etc.).1
  • ¶¶SKINVIVE™ should not be used simultaneously with laser treatment, deep chemical peels or dermabrasion. For surface peels, it is recommended not to inject the product if the inflammatory reaction generated is significant.1
  • ***Data derived from a prospective, non-randomised, interventional, open-label study where 11 healthy patients (men [n=2] and women [n=9]) received intradermal VYC-12L treatment on the volar forearm. Clinical probes assessed skin quality at baseline and Months 1 and 3 post-treatment. Punch biopsies were collected at Months 1 and 3 post-treatment to evaluate histologic and genomic changes.14
  • †††Individual results may vary.

References

  1. SKINVIVE™ by JUVÉDERM® DFU. 20081699. Revision 2023-10-04.
  2. Ogilvie P et al. J Cosmet Dermatol. 2020;19(5):1065–1070.
  3. Niforos F et al. Clin Cosmet Investig Dermatol. 2019;12:791–798.
  4. Purnamawati S et al. Clin Med Res. 2017;15(3-4);75–87.
  5. Allergan Aesthetics. Data on File. Juvéderm® VOLITE Treatment Area. REF-80815. March 2019.
  6. Alexiades M et al. Dermatol Surg. 2023;49(7):682–688.
  7. Akinbiyi T et al. Plast Reconstr Surg Glob Open. 2020;8(10):e2763.
  8. Lipko-Godlewska S et al. Clin Cosmet Investig Dermatol. 2021;14:169–178.
  9. Khmaladze I et al. Clin Cosmet Investig Dermatol. 2020;13:1021–1040.
  10. Zarbafian M et al. Dermatol Surg. 2022;48(3):369–372.
  11. Humphrey S et al. Dermatol Surg. 2021;47(7):974–981.
  12. Belmontesi M, et al. J Drugs Dermatol. 2018 Jan 1;17(1):83-88.
  13. Safa M et al. Clin Cosmet Investig Dermatol. 2022;15:411–426.
  14. Draelos Z. J Clin Aesthet Dermatol. 2012;5(7):53–56.
  15. Allergan Aesthetics. Data on File. SKINVIVE™ by JUVÉDERM® – 9-month duration of skin hydration in clinical trials. REF-108945. March 2023.
  16. Ogilvie P et al. Clin Cosmet Investig Dermatol. 2020;13:267–274.

The information on this website is intended for informational and educational purposes only and should not be used as a substitute for advice provided by a qualified aesthetic healthcare professional.

Models received a variety of JUVÉDERM® products, including SKINVIVE™ by JUVÉDERM®. Images provided courtesy of Allergan Aesthetics, an AbbVie company (unless stated otherwise). Actual treatment results may vary. Images are for illustrative purposes only.

Website produced and funded by Allergan Aesthetics, an AbbVie company.

IMPORTANT SAFETY INFORMATION

This content is intended for UK and Irish adult (>18yrs) audiences only. You should always consult a healthcare professional to help you decide if SKINVIVE™ by JUVÉDERM® is right for you and provide you with a full list of potential side effects.

Potential side effects associated with SKINVIVE™ by JUVÉDERM® include temporary injection-site reactions such as redness, swelling, itching, pain, firmness, bumps, bruising, and discolouration. These reactions may occur immediately or may be delayed. As with any injection, there is a risk of infection. This is not a complete list of side effects. If inflammatory reactions persist for more than one week, or if any other side effects develop, seek medical attention as soon as possible.4

Please refer to SKINVIVE by JUVÉDERM® Directions for use (DFU) for a full list of indications, contraindications, precautions for use, and adverse events.

Adverse events should be reported.

 

Reporting of side effects:

UK patients: If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in the package leaflet. You can help by reporting side effects directly via the Yellow Card Scheme at https://yellowcard.mhra.gov.uk/ or via the MHRA Yellow Card app, available in the Google Play or Apple App Stores. Adverse events should also be reported to AbbVie at ProductSurveillance_EAME@allergan.com. By reporting side effects, you can help provide more information on the safety of this product.

 

Irish patients: If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in the package leaflet. You can also report side effects directly via www.hpra.ie.

UK-SKV-250025 | September 2025